This book presents cutting-edge research and developments in the broad field of medical, biological engineering and computing. Second volume of the proceedings of the XVII Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON 2026), held on September 14-17, 2026, in Siena, Italy, it bridges between device innovation and clinical practice. Contributions cover advances in wearable and remote sensing systems for continuous patient monitoring, topics in healthcare management and medical device design, and developments in biomaterials for drug delivery, tissue regeneration, and other medical applications. They offer extensive and timely information to biomedical and materials engineers, robotics engineers, and healthcare professionals.