The absence of participation in physical activity is a public health concern for all people, but even more of a problem for the estimated 52 million Americans with disabilities (Rimmer 2005). The focus of this research is investigating how trail planning and design in natural settings can better provide for the physical, sensory, and cognitive experience of users, particularly those users who have disabilities. Findings informed the development of Natural Trail Design Guidelines prepared for the City of Manhattan Parks and Recreation Department who is seeking to improve the Citys existing natural trails. Sample designs for trail enhancements at Anneberg Park and the Konza Prairie near Manhattan, Kansas were proposed. Once implemented and assessed to be found successful, the Natural Trail Design Guidelines might be transferable to other locations.